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At 3 nmol/kg SC, wild-type mice lost approximately 3.4 g body weight versus no significant loss in vehicle-treated controls

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In lung cancer models, lutein was found to induce apoptosis by modulating PI3K/Akt signaling, effectively inhibiting Akt to trigger cancer cell death while sparing normal cells ( 3.2.4 Carotenoids: oxidative stress and miRNA networks Lycopene modulates oxidative stress-responsive miRNAs in prostate cancer through antioxidant pathways

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Springer, Heidelberg, pp 4572 Lange SC, Bak LK, Waagepetersen HS, Schousboe A, Norenberg MD (2012) Primary cultures of astrocytes: their value in understanding astrocytes in health and disease