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The structure of NADP + similar to that of NAD + renders its binding to PARPs

207 A RANDOMIZED CONTROLLED TRIAL COMPARING SUSTAINED LOW EFFICIENCY DIALYSIS WITH CONTINUOUS RENAL REPLACEMENT THERAPY FOR SEPSIS-ASSOCIATED ACUTE KIDNEY INJURY IN CRITICALLY ILL PATIENTS WITH CIRRHOSIS (NCT04494542) Rakhi Maiwall 1 , Neha Chauhan 2 , Ashinikumar Kumar Hidam 2 , Sherin Thomas 2 , Chandani Bhagat 2 , Prashant Aggarwal 2 , Shivali Panwar 2 , Harsh Vardhan Tevethia 1 and Shiv Kumar Sarin 3 , (1)Institute of Liver and Biliary Sciences, New Delhi, (2)Institute of Liver and Biliary Sciences, (3)Ilbs Background: Continuous renal replacement therapy (CRRT) is the preferred mode of dialysis in critically ill hemodynamically unstable patients and in addition removes the inflammatory cytokines that accumulate in sepsis

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Kurz T, Yamada KA, DaTorre SD, Corr PB