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Xu et al., 2011

However, the clinical effectiveness of these approaches remains to be determined

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The role of oxidative stress in the pathogenesis of IBD is well-documented, with high levels of reactive ROS and RNS contributing to gut mucosal damage and the activation of inflammatory pathways

The Pfizer-BioNTech, Moderna, and Johnson & Johnson COVID-19 vaccines are presently approved for emergency use and are recommended for pregnant women after consultation with a healthcare provider

For example, prolonged ferroptosis inhibition may promote tumorigenesis (by suppressing cell death in pre-malignant cells) or exacerbate other pathological processes (e.g., fibrosis) in ADPKD kidneys, risks that require rigorous evaluation in long-term animal models