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IRI is the most common pathogenesis that induces AKI in clinics, and generally occurs in the cerebrum, intestines, heart, lungs, and liver, during which process ferroptosis plays a vital role

Exposure to increasing NAC concentrations also induced a dose-dependent reduction of cell index, although reduced compare to the effects of GSH (Figure 1B)

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Glutathione is a potent antioxidant composed of three amino acids: glutamine, cysteine, and glycine