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The compound binds HGF with sub-nanomolar affinity (Kd 65 pM) and is investigated as a synaptogenic research molecule with notable properties unusual for a peptide: oral bioavailability and blood-brain barrier permeability

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10.1016/j.addr.2022.114449 Summary Keywords Parkinsons disease, dopaminergic neurons, nano-structured technologies, nanomedicine, targeted drug delivery, neuroprotection, neurodegeneration, progressive neurodegenerative disorder Citation Prasanth MI, Mallya AR, Cho WC and Mundekkad D (2025) Nano-structured strategies in combatting neurodegeneration