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The reason storage discipline matters more here than for a single-use peptide is arithmetic: because one vial spans several once-weekly doses over potentially a month, the solution has to hold potency across that entire window

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This data can be found here: Ethics statement The studies involving human participants were reviewed and approved by the Ethics Committee of Peking Union Medical College Hospital

Lithocholate (bile acid), urobilin (bilirubin metabolite), n-acetylglutamate (ammonia cycle and arginine biosynthesis) and caproic acid (active metabolite) were enriched in all the groups apart from T3, and both citrulline (arginine precursor) and phenylacetate (amino acid metabolism) were enriched in all the groups apart from T2