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The notable molecular pathways targeted by black cumin and TQ are Nrf2, NF-B, TLR, SIRT1, AMPK-SIRT1-PGC-1, PPAR, and PI3K/Akt signaling, which are shared across health/disease conditions (Figure 6)

Med Razgledi 1982;21:323-328

Nie X, Shen C, Tan J, et al

Ongr D, Price JL

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We also found SlUGT gene could participate in plant detoxification through interaction with transcription factors, which conferred a new direction for studies on the function of the SlUGT gene