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G.JanezA.StoianA

J.GilaniA

Similarly, treatment with an HMGB1 monoclonal neutralizing antibody can alleviate the phenotype of MRL/ lpr and BXSB Lupus mice, but it has also been shown to be ineffective in MRL/ lpr mice ( Extracellular HMGB1 is derived mainly from cell death, including apoptosis, necroptosis and ferroptosis (165)