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Salonen M, Sulkama S, Mikkola S, et al

Roughly 25-40% of total weight lost on GLP-1-class drugs is lean mass , and retatrutide's fat-to-lean ratio in trials is comparable to semaglutide and tirzepatide most of what you lose is fat

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From my experience working closely with skincare manufacturing partners, I have seen how the success of these products often depends not only on the ingredient itself but also on the expertise of the manufacturer behind the formulation