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biologic therapy initiation Severe/fulminant: IV corticosteroids (methylprednisolone 4060 mg/day IV)

Using B12 sprays or injections can help boost energy levels in those who have low levels of vitamin B12

Vegans and vegetarians are at risk of B12 deficiency because its mostly found in animal products

Deltoid, vastus lateralis, or gluteus

Occupational therapy and sensory integration strategies help children develop better coping skills and improve their daily functioning

In Noonans syndrome genetic defects in the PTPN11 gene may affect this pathway and has been implicated in poor growth and poor response to GH therapy, although reports are conflicting (99, 100)