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Instead, inoculation with BacA induced a greater upregulation of proinflammatory cytokines than IcL and wild-type in both models and a greater expansion of cytotoxic and memory T-cells than uninfected control in calves

When NNMT is overactive, it consumes S-adenosylmethionine (SAM) and reduces levels of nicotinamide adenine dinucleotide (NAD+), a critical coenzyme involved in cellular energy production

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