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This Echi-E, primarily composed of chicoric acid and dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamide, decreased the frequency and relative expression of molecules involved in antigen presentation (MHC class II) and co-stimulation (CD86 and CD54), as well as the activity of COX-2

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Mortensen et al., 2012

The influx of cytoplasmic iron into mitochondria and the utilization of the free iron were mediated by mitoferrin, endosomes, or other mechanisms [78]