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Nanomaterials 15 (2), 126

Reduced BDNF availability may in turn limit TrkB phosphorylation and attenuate downstream PI3K/Akt and MAPK/ERK signaling (Numakawa and Kajihara, 2023)

The commonly used chemotherapy TMZ not only blocked autophagy induced by BT317 in vitro but also showed enhanced synergy with BT317

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To further validate the findings, the experiment was repeated using a different antibiotic, Tobramycin

However this elution is slow and generally results in broad solute peaks