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A recent study identified deleterious changes in the left ventricular structure leading to cardiovascular dysfunction and increased systemic arterial resistance [96]

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**Reductions in levels of the 9 harmful chemicals the World Health Organization recommends to reduce in cigarette smoke, which do not include nicotine

Refillable vape kits in the UK cost on average 320 per year in 2026 (rising to roughly 480 once the Vaping Products Duty lands on 1 October 2026), making them over 85% cheaper than smoking 10-a-day

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Researchers analyzed 1,047 tobacco ads for combustible cigarettes, smokeless tobacco, little cigars and cigarillos, and electronic nicotine delivery systems (ENDS) including e-cigarettes and heated tobacco products that circulated between January 2018 and December 2020