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Caspase-8 then triggers caspase-3, resulting in apoptosis

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Walther D.J., Bader M

5 The absolute risk increase is small (around 3 extra cases for every 1,000 people taking the medication for a year), and the effect is partly explained by weight loss rather than the medication itself