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While antioxidant systems can mitigate oxidative injury to healthy tissues during breast cancer treatment, indiscriminate use of exogenous antioxidant supplements during ROS-dependent therapies such as anthracycline chemotherapy and radiotherapy may theoretically reduce treatment efficacy by protecting malignant cells from oxidative damage

Molecular mechanism of nrf2 activation by oxidative stress

Plasma levels of total protein (TP), albumin (ALB), aspartate aminotransferase (AST), alanine aminotransferase (ALT), cholesterol (CHOL), triglycerides (TRIGL), high-density lipoproteins (HDL), low-density lipoprotein (LDL), uric acid (UA), creatinine (CREJ) and glucose (GLU) were measured using automated analyser (Cobas c111 Analyzer, Roche Diagnostics)

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Angiotensin-II type 1 receptor-mediated hypertension in D4 dopamine receptor-deficient mice