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Trimethylamine-N-oxide, as a risk factor for atherosclerosis, induces stress in J774A.1 murine macrophages

J., Gmez, A

We know that clogged coronary arteries can lead to heart attacks

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We found that primary cultured mouse tubular cells exposed for 24 h to colistin at an extracellular concentration of 100 M indeed displayed mitochondrial and ER damage, and that both were prevented by co-incubation with 1 mM L-carnitine