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A Possible Role for 5-Amino-1MQ in Cognition NAD+ is essential for energy homeostasis within the brain and for communication across synaptic junctions

For instance, CART knockout (KO) mice exhibited lower alcohol preference than wild-type mice 28 , moreover low alcohol-preferring DBA/2J mice show decreased CART mRNA and peptide expression in the EWcp compared to alcohol-preferring C57BL/6J mice 17