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42 In most tissues, the leukocyte recruitment follows a well-characterized cascade of sequential steps, including tethering, rolling, firm adhesion, intravascular crawling, and transendothelial migration

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Ajithkumar T, Parkinson C, Fife K, Corrie P, Jefferies S (2015) Evolving treatment options for melanoma brain metastases

Hereditary conditions like asthma or allergies can also increase the risk

Haematologica, 2010

NR1D2-mediated PNPLA2/ATGL inhibition disrupts the lipid metabolism of macrophages in the human body, leading to lipid accumulation and weakening the effect of autophagy on Burkholderia pseudomallei immunity to infection, leading to the continued development of infection (Tang et al., 2021)