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It has been well known that most cancer cells predominantly generate energy by a high rate of glycolysis followed by lactic acid fermentation in the cytosol, rather than by a comparatively low rate of glycolysis followed by oxidation of pyruvate in mitochondria like most normal cells

However, AMPK, a key regulator of multi-pathways and multi-targets, also gets involved in inflammation mitigation, Ca 2+ -handling and cell contraction, mitochondrial biogenesis, cell growth and proliferation, and so on, thus exerting cardiovascular protection with a combination of multiple mechanisms (Garcia and Shaw, 2017)

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Effects of omega-3 fatty acids in prevention of early preterm delivery: a systematic review and meta-analysis of randomized studies

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