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Furthermore, additional COVID-19 vaccines utilizing lipid nanoparticle-mRNA formulations are currently undergoing assessment in various clinical phases [83]

(2002) and Whitmore and Wallace (2004), available through the DichroWeb platform ( Total polyphenol content (TPC) Samples were extracted with 80% methanol or 50% methanol or sequentially using 80% methanol, 50% methanol and 70% acetone followed by TPC determination by the Folin-Ciocalteu method as previously described (Agboola et al., 2010)

4.3 Antioxidant effect The imbalance between the production and clearance of reactive oxygen species (ROS) or free radicals leads to oxidative stress, as ROS are natural byproducts of biological oxygen metabolism (Palma et al., 2024)

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Ca 2+ is a master regulator of eryptosis, mediating the Gardos effect-associated RBC dehydration and reduction of cell volume (cell shrinkage), calpain activation-mediated cytoskeleton remodeling (membrane blebbing), and PS externalization, which are major hallmarks of eryptosis