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What a Herxheimer Reaction Feels Like Patients experiencing a Herxheimer reaction may report: Increased fatigue Worsening brain fog Muscle or joint pain Flu-like symptoms Sleep disruption Dizziness or head pressure Mood shifts or anxiety These symptoms can resemble a flare-up or relapse, which adds to the confusion

Toxicology 328 , 1220 (2015)

Immunofluorescent stainings For staining of tissue sections, human and murine lung tissue was fixed in 4% formalin prior to paraffin embedding

BSE resulted in a 0.2 mmol/L reduction in fasting blood glucose compared to placebo (95% confidence interval -0.44 to -0.01, p=0.04), which did not meet the predefined outcome of 0.3 mmol/L

2.5 Immune dysfunction In UC, intestinal inflammation is driven by sustained dysregulation of both innate and adaptive immunity, which together propagate and amplify mucosal injury (Yue et al., 2024)

Zhou Y, Wang Z, Huang Y, Bai C, Zhang X, Fang M, Ju Z, Liu B (2022c) Membrane dynamics of ATG4B and LC3 in autophagosome formation