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The Difficulties With Vitamin B12 A 22-year-old woman presented with progressive sensory ataxia and optic neuropathy

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One in vitro analysis of interactions between retinols and cytochrome P450 found that a high retinol dose could inhibit CYP2C19 [302], one of the CYPs responsible for the 7-hydroxylation of the warfarin R-isomer [72] (Figure 3)

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