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Efficacy of VCDs is unclear due to the lack of high-quality studies, but it has been estimated at 35% to 90%

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They also found that the regulation of NSC proliferation by KIAA1549-BRAF was mediated by mTOR signaling (66)

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Activation of protein kinase C-zeta and phosphatidylinositol 3'-kinase and promotion of macrophage differentiation by insulin-like growth factor-I