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Description

Tregs in T1D T1D is the most prevalent autoimmune disease in humans and is caused by the immune system targeting insulin-producing -cells, resulting in impaired insulin secretion and ineffective glucose utilization, ultimately leading to hyperglycemia

10.1046/j.1471-4159.2000.0742622.x 2 BaiL.XuH.CollinsJ

E.g., if a receptor has more than one binding site for a ligand, a ligand having low affinity can be useful for targeting the microvascular endothelium