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Treatment Vitamin B12, in the forms of cyanocobalamin and hydroxycobalamin, can be administered parenterally as a prescription medication, usually by intramuscular injection

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You may be given a pain diary to record what you feel for several hours after the injection

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An orthopedic specialist will conduct a thorough evaluation, which may include physical exams, imaging tests, and laboratory work, to diagnose the underlying cause of your leg pain at night