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Human clinical trials are limited

doi:10.1007/BF00581375 PMID: 568769 3

FOXO4 is a forkhead box O transcription factor that mediates various signaling pathways to maintain cellular homeostasis 33

Initially developed to promote nerve outgrowth, this peptide is now being studied for its ability to improve brain health and support neuroregenerative processes

2021 (PMID 34827486), published in Brain Sciences by a Chinese research group with no tie to the WSU lab, tested Dihexa in APP/PS1 transgenic mice a standard Alzheimer's disease model