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10.1038/s41467-018-06004-8 173 SieghartW.SperkG

A deficiency can lead to fatigue, increased susceptibility to infections, or muscle weakness

Primary endocrine resistance was defined as relapse while on the first 2 years of adjuvant endocrine therapy (ET) and secondary endocrine resistance was defined as relapse while on adjuvant ET after at least 2 years or relapse within 12 months of completing adjuvant ET

reports indicate induction of NO signaling and eNOS-linked vasodilatory effects, which may underlie faster perfusion and healing

Then review how vitamin B12 deficiency relates to depression

Impact of oxidative stress on age-associated decline in oocyte developmental competence