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10.12729/jbr.2012.13.1.65 45 ChenM.Aoki-UtsuboC.KameokaM.DengL.TeradaY.KamitaniW.et al (2017)

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Subsequent intravenous (IV) administration to both mammalian liver cell-lines (HepG2) in vitro and CTLN2 mouse model in vivo corrected the subcellular localisation and expression of a fully functional citrin protein in liver mitochondria, i.e., almost equivalent to 25% of wild-type expression levels [134]

Side effects and safety BPC-157 appears to be well-tolerated in research studies

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Candidate SARS-CoV vaccines formulated with either alum, CpG or Advax (a delta inulin-based adjuvant) found that while the Th2-biased responses associated with alum drove lung eosinophilic immunopathology in mice, protection without immunopathology and a more balanced Th1/Th2 response were induced by Advax 62