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The Journal of Pharmacology and Experimental Therapeutics issued an Expression of Concern in 2021 (PMID: 34551989) for the McCoy et al

"Prospective Alzheimer's drug builds new brain cell connections, improves cognitive function of rats"

Standard laboratory handling involves lyophilized 20 C storage, reconstitution in sterile or bacteriostatic water, and aliquoting to limit freeze-thaw cycles

Protocol 2: intensive 10-day cycle Goal: Concentrated telomerase activation with reduced injection frequency Duration: 10 days active, then 4-6 months off Schedule: Days 1-10: 10 mg epitalon subcutaneously, once daily at bedtime Days 11-180: Off cycle Repeat cycle 1-2 times per year Reconstitution: 10 mg vial plus 1 mL bacteriostatic water equals 10 mg/mL

It is not approved for human therapeutic use in Australia and is not for human or animal consumption

Animal Model:NMRI-Hannover (male, 30 g, deep partial skin thickness burns induced by 5 s direct flame exposure covering 20% total body area) [2] Dosage:i.p.: 10 ng/kg, 10 g/kg