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Moreover, BaP metabolite BPDE could induce DNMT3a binding to the promoters of related tumor suppressor genes, which resulted in the aberrant methylation of retinoic acid receptor-2 (RAR-2) in human esophageal cancer cells, and BPDE reduced DNMT3b expression [153]

FIGURE 3 3.3 GHK-Cu promoted mucosal healing GHK-Cu treatment significantly enhanced of ZO-1 and Occludin expression in colitic mice, which were downregulated by DSS (Figures 4AC)

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Zhao C, Zhang Y, Liu H, Li P, Zhang H, Cheng G

Estimation of Glutathione Level in Second Trimester of Pregnancy