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To assess whether the HIF-dependent potentiation of cell death is due to synergizing with compounds that reduce GSH pools, we used buthionine sulfoximine (BSO), which inhibits de novo GSH biosynthesis

Interestingly, short-term incubation with FLT3i strongly depleted C/EBP protein expression without modification of its inhibitory phosphorylation at Ser21 (ratio P S21 -C/EBP / total C/EBP p42

It plays a crucial role in regulating and boosting the immune system's response to pathogens, infections, and diseases

USA 104 , 55635568 (2007)

Only trained professionals should handle this compound under safe laboratory conditions

2011 Jan;409(1):46-53