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The penis typically regresses back to a flaccid state with lack of stimulation, sympathetic overdrive, or normal post ejaculatory physiology

JAMA Psychiatry 82 , 9498 (2025)

these small somatic fibres have sensory functions including thermal perception and nociception

Indeed, in vivo human and rodent studies demonstrated that treatment with the DA precursor L-DOPA causes hyperglycemia due to decreased GSIS 11,12,13,14