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What it does establish is biological plausibility for restoration: putting back what the body has lost is a more conservative pharmacological proposition than overdriving a healthy system

40 In addition to the above regulatory factors, crosstalk between Wnt/-catenin and other pathways also regulates canonical Wnt signalling in different ways (Table 4)

Understanding these molecular pathways is key to developing future therapies that could slowor preventvision-threatening scarring

M.Correia GuedesL.CoelhoM.RosaM

Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

Krishna MC et al (1998) Studies of structure-activity relationship of nitroxide free radicals and their precursors as modifiers against oxidative damage