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A preclinical safety evaluation published in ScienceDirect confirmed that BPC-157 caused mild local irritation but demonstrated good overall tolerance across mice, rats, rabbits, and dogs

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Studies have demonstrated measurable lipolytic activity in adipose tissue while confirming the absence of significant changes in blood glucose, insulin sensitivity, or IGF-1 levels, validating its utility as a targeted research tool for studying fat metabolism pathways independently of growth axis effects

Cell Host Microbe (2018) 23:71624