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Conclusions Despite advancements in our understanding of DN, addressing the growing healthcare burden posed by this complication of diabetes remains challenging

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Of these seven groups, the Firmicutes , Proteobacteria , and Verrucomicrobia phyla demonstrated a significant main effect of treatment group on relative abundance after BenjaminiHochberg correction for multiple comparisons, while Bacteroidetes and Actinobacteria demonstrated significant main effects of treatment group on relative abundance before BenjaminiHochberg correction

These cells release IL-10 and TGF-, which suppress DC maturation and function, ultimately impairing CD8 T-cell priming

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