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3.1.3 Purine nucleoside derivant: Clofarabine Clofarabine ( 3 ) is a purine nucleoside DNMTi, which was approved by the FDA in 2004 for the treatment of refractory or relapsed AML in children with the trade name of clofarabine

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Most longevity peptides target one or two biological pathways

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10.1016/j.chemgeo.2008.01.022 88

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To investigate whether the action of NAC in growth arrest is related to its antioxidant property via intracellular GSH, we treated GBM cells with BSO in the presence of NAC and cell viability was analyzed

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In this respect, it would be interesting to analyze the interactome of Set7/9 in these cells to see whether it can physically bind chromatin modifying enzymes

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