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and (2) presynaptic M1 autoreceptor blockade on vagal nerve terminals , which removes negative feedback and transiently increases acetylcholine release (Kawashima et al 1988)

DNA Repair 42:6371 Kaufmann HE (2008) Paul Ehrlich: founder of chemotherapy

Alcohol is classified as a drug and is a known depressant

The FDA Adverse Event Reporting System shows a likely link between GLP-1 RAs (specifically liraglutide) and increased risk of pancreatitis

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When blood sugar is extremely elevated, the kidneys reabsorb less glucose and consequently less water, which may cause severe (and potentially fatal) dehydration