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Patients with RLS often complain of an almost irresistible urge to move their legs

21 Central disinhibition Central disinhibition refers to an imbalance between the excitatory and inhibitory side of the nervous system, such that there is reduced inhibition to the spinal cord dorsal horn

The all-cause mortality may be more than twice as high in current smokers with CKD compared with those who never smoked

doi: 10.1159/000506879CrossRefGoogle ScholarPubMed Chanson, P., Arnoux, A., Mavromati, M., Brailly-Tabard, S., Massart, C., Young, & J., for the VARIETE Investigators (2016)