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Most people start with around 200-400 mcg per day, but this can vary depending on your goals and needs

For its part, FDA proposed a pilot program where qualified external institutions can collaborate with sponsors to develop and review protocols for first-in-human (FIH) clinical trials intended for investigational new drug (IND) submissions, and several associated draft guidances, including one clarifying when developers can rely on one rigorous, adequate, and well-controlled clinical trial, along with confirmatory evidence, to support drug approvals

William Seeds, author of Peptide Protocols, recommends 100mcg administered approximately 3 hours before bedtime

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