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Reciprocally, gut microbiota biotransform dietary components to produce various physiologically active metabolites, such as SCFAs, secondary bile acids, and indole derivatives, which enter the liver via the portal venous system and participate in host glucose and lipid metabolism as well as immune regulation ( The concept of the gut-liver-kidney nutritional metabolic axis has gradually emerged and received widespread attention in recent years

Drug deposition is a highly intricate process that is affected by some variables, like the drug's particle size, location, and rate of deposition [24]

Manganese restriction in parenteral nutrition for preterm neonates: a pilot randomized controlled trial

10.1002/ana.22052 83 Garca-CasaresN.Gallego FuentesP.BarbanchoM.Lpez-GigososR.Garca-RodrguezA.Gutirrez-BedmarM

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During the late exponential growth phase, MCFA intermediates are released prematurely from the cytoplasmic fatty acid synthase (FAS) complex, and this release triggers ester synthesis (Taylor and Kirsop 1977)