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Metabolic reprogramming of cancer cells is now recognized as a hallmark of cancer [3]

N Engl J Med 370:583 Thim T, Krarup NH, Grove EL, Rohde CV, Lfgren B (2012) Initial assessment and treatment with the airway, breathing, circulation, disability, exposure (ABCDE) approach

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Cornall RJ, Adams R, Kato M, Nelms KA, Hong NA, Florin TH, et al

Consistent with earlier reports (Han et al., 2013), analysis of the glutathione-deficient pad2-1 plants demonstrated that 30% of the wild-type glutathione level is enough to sustain ascorbate recycling during high-light exposure