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The role of tumor-associated neutrophils in colorectal cancer

Therapeutic strategies for targeting ferroptosis It has been over a decade since the term ferroptosis was first introduced, and as research has advanced, several clinical drugs and bioactive pharmacological agents have been identified as modulators of ferroptosis, including inhibitors (Table 2) [113,114,115,116,117,118,119,120,121,122,123,124,125] and inducers (Table 3) [126,127,128,129,130,131,132,133,134,135,136,137,138,139,140]

Paraffin sections of 3 mm samples were prepared on a paraffin microtome

Nishigori H, Hayashi R, Lee JW, et al

Cancer 4 , 344364 (2023)

Although a huge number of experimental and preclinical investigations have provided encouraging results, clinical trials must be performed and completed to definitely evaluate the usefulness and risks of targeting IGF-1R as an option in cancer treatment of humans