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doi: 10.1105/tpc.111.091033

Our results indicate that the inhibition of SKN-1 is one of the major causes of accelerated aging by exogenous thiols, as NAC shortened the lifespan of daf-16 animals, but failed to do so for skn-1 mutants (Figs

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Specifically, the study involved engineered cells implanted in eight C57BL/6 J female mice, successfully delivering cargo mRNA to the brain

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