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It is a paradigm shift

First description of the surgical anatomy of the cynomolgus monkey liver

Kaiyala, K

Jimmy Gutman

314,315,316 An increase in peroxisome proliferator activated receptor gamma 2 (PPAR2) and upregulation of hippocampal catalase in KD-fed rats are observed, which may increase anti-inflammatory and antioxidant activity

Concurrently, a significant increase in NADH/NAD + ratio ( P = 0.0002) was observed (Figure 6C), suggesting that the observed metabolic disruptions were a result of oxidative stress, potentially as a compensatory mechanism to sustain energy production and redox homeostasis in the absence of GR