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Safety in controlled studies: Minimal systemic hormonal effects simplify interpretation of fat-specific pathways

These limitations dont invalidate the positive safety findings but do suggest that comprehensive medical supervision remains appropriate for anyone using AOD-9604, particularly for off-label applications or extended treatment periods

These approaches are mechanistically complementary one adds substrate, the other prevents its degradation

It is not an authorised UK medicine or an established weight-management treatment

This decline can impair physical function and mobility

Approximately 900 adult participants were enrolled across six randomized, double-blind, placebo-controlled clinical trials conducted between 2001 and 2006