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Intracellular glutathione levels of T cells cocultured with dendritic cells or fibroblasts pretreated with sulfasalazine

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Among these agents, CB-839 is the only one to proceed to clinical trials

10.1111/j.2047-2927.2013.00096.x 73

Different studies have shown that ZEN has toxic effects both in vivo and in vitro, and in vivo the main target organ of action is the reproductive organ, which can induce endoplasmic reticulum (ER) stress-mediated apoptosis in leukemic cells [100]

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