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Age- and disease state-dependent changes in endogenous levels of neurosteroids appear to play a role in the emergence of the unique functional imbalances implicated in specific neuropsychiatric disorders and the associated memory deficits, which are mediated in part by changes in neural network activity within specific brain regions implicated in the encoding, consolidation, and retrieval of memories

DOI: 10.1056/NEJMoa2502081 Davies MJ, Bajaj HS, Broholm C, Christiansen E, Fink LN, Hussein Z, et al

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1987;37(Suppl 1):360

Cagrilintide monotherapy weight loss In the phase 2 trial over 26 weeks, cagrilintide weight loss ranged from 6.0% to 10.8% of body weight depending on dose

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