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Baseline demographic and other characteristics, vital signs, clinical laboratory findings, 12-lead ECG results, and treatment-emergent AEs (TEAEs) were summarized for the safety analysis set, which consisted of all participants who received the study drug

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However, because cancer cells have fewer error-correcting capabilities, they are affected much more than healthy cells

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A design-space generator enumerates feasible trains under compatibility rules, such as carbon diversion vs nitrification trade-off, then evaluates them via hybrid simulation, mechanistic ASM/AnMBR models coupled to machine-learning metamodels