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TGF-, transforming growth factor-beta

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*Correspondence: Dingxin Long, [email protected] This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Generative AI statement The authors declare that Generative AI was not used in the creation of this manuscript

Without proper treatment, this closed environment can intensify the buildup over time